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Rabbit Anti-Human PTEN Monoclonal Antibody (Clone SP218)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07067640001
0.1 mL

Product No. Pack Size
07067674001
1.0 mL


Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and a member in the PI3K/PTEN/Akt pathway. The defects of PTEN have been implicated in human cancers from breast, prostate, thyroid, skin, endometrium, head and neck, and brain. Up to 50-60 percent of advanced prostate cancers show abnormal PTEN gene expression or loss of protein expression.

Figure above:
Human prostate adenocarcinoma stained with anti-PTEN antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Colon adenocarcinoma stained with anti-PTEN antibody

Human Colon adenocarcinoma stained with anti-PTEN antibody2

Human Human Colon adenocarcinoma stained with anti-PTEN antibody3

Human Colon adenocarcinoma stained with anti-PTEN antibody4

Human Colon adenocarcinoma stained with anti-PTEN antibody

Human Colon adenocarcinoma stained with anti-PTEN antibody

Human Colon adenocarcinoma stained with anti-PTEN antibody

Human Colon adenocarcinoma stained with anti-PTEN antibody

Human Colon adenocarcinoma stained with anti-PTEN antibody5

Human Colon adenocarcinoma stained with anti-PTEN antibody6

Human Colon adenocarcinoma stained with anti-PTEN antibody7

Human Colon adenocarcinoma stained with anti-PTEN antibody8

Human Colon adenocarcinoma stained with anti-PTEN antibody

Human Colon adenocarcinoma stained with anti-PTEN antibody

Human Colon adenocarcinoma stained with anti-PTEN antibody

Human Colon adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody9

Human Prostate adenocarcinoma stained with anti-PTEN antibody11

Human Prostate adenocarcinoma stained with anti-PTEN antibody12

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody13

Human Prostate adenocarcinoma stained with anti-PTEN antibody14

Human Prostate adenocarcinoma stained with anti-PTEN antibody15

Human Prostate adenocarcinoma stained with anti-PTEN antibody16

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody17

Human Prostate adenocarcinoma stained with anti-PTEN antibody18

Human Prostate adenocarcinoma stained with anti-PTEN antibody19

Human Prostate adenocarcinoma stained with anti-PTEN antibody20

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody21

Human Prostate adenocarcinoma stained with anti-PTEN antibody22

Human Prostate adenocarcinoma stained with anti-PTEN antibody23

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody



Flow Cytometric Analysis


Flow cytometric analysis of rabbit anti-PTEN (SP218) antibody in A431 (green) compare to negative control of rabbit IgG (blue)

Flow cytometric analysis of rabbit anti-PTEN (SP218) antibody in A431 (green) compare to negative control of rabbit IgG (blue)



Western Blot Analysis


Western Blot analysis of HeLa Cell Lysate with PTEN antibody

Western Blot analysis of HeLa Cell Lysate with PTEN antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP218

Application

IHC-P, WB, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Dg, Fg, Ms

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from the C-terminus of human PTEN protein.

Cellular Localization

Cytoplasm, Nucleus

Control Tissue

Prostate, Prostate Adenocarcinoma

Regulatory Rating

Research Use Only (RUO)

Entrez

5728

Storage Requirement

2-8°C

Target Molecular Weight

54 kDa

Formulation

Refer to Data Sheet

Product No: 07067640001
Product No: 07067674001

Rabbit Anti-Human PTEN Monoclonal Antibody (Clone SP218)

Poster (PDF, 2.01 MB)

Rabbit Anti-Human PTEN Monoclonal Antibody (Clone SP218)

Instructions for Use (PDF, 93.71 KB)
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