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Rabbit Anti-Human PTEN Monoclonal Antibody (Clone SP170)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06771050001
0.1 mL

Product No. Pack Size
06771076001
1.0 mL


Phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase (PTEN) is a tumor suppressor and a member in the PI3K/PTEN/AKT pathway. PTEN is a phosphatase with dual specificity to slow cell growth and antagonize the growth promoting activities from HER protein kinases. The defects of PTEN, mostly around the C-terminus of PTEN, have been implicated in many human cancers and diseases. Therefore, antibody to the N terminus will not be able to detect most of the PTEN protein loss. **Please contact us for availability**

Figure above:
Human prostate adenocarcinoma stained with anti-PTEN antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Cervical Squamous Cell Carcinoma stained with anti-PTEN antibody

Human Colon Adenocarcinoma stained with anti-PTEN antibody

Human Lung Squamous Cell Carcinoma stained with anti-PTEN antibody

Human Ovarian Carcinoma stained with anti-PTEN antibody

Human Cervical Squamous Cell Carcinoma stained with anti-PTEN antibody

Human Colon Adenocarcinoma stained with anti-PTEN antibody

Human Lung Squamous Cell Carcinoma stained with anti-PTEN antibody

Human Ovarian Carcinoma stained with anti-PTEN antibody

Human Ovary stained with anti-PTEN antibody

Human Prostate Adencarcinoma stained with anti-PTEN antibody

Human Prostate Adencarcinoma stained with anti-PTEN antibody

Human Prostate  adenocarcinoma stained with anti-PTEN antibody

Human Ovary stained with anti-PTEN antibody

Human Prostate Adencarcinoma stained with anti-PTEN antibody

Human Prostate Adencarcinoma stained with anti-PTEN antibody

Human Prostate adenocarcinoma stained with anti-PTEN antibody

Human Prostate Adenocarcinoma stained with anti-PTEN antibody

Human Prostate stained with anti-PTEN antibody

Human Stomach Adenocarcinoma stained with anti-PTEN antibody

Human Prostate Adenocarcinoma stained with anti-PTEN antibody

Human Prostate stained with anti-PTEN antibody

Human Stomach Adenocarcinoma stained with anti-PTEN antibody



Flow Cytometric Analysis


Flow cytometric analysis of rabbit anti-PTEN (SP170) antibody in A431 (green) compare to negative control of rabbit IgG (blue)

Flow cytometric analysis of rabbit anti-PTEN (SP170) antibody in A431 (green) compare to negative control of rabbit IgG (blue)



Western Blot Analysis


Western Blot analysis of MCF-7 cell lysate with PTEN antibody

Western Blot analysis of MCF-7 cell lysate with PTEN antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP170

Application

IHC-P, WB, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Dg, Ms

Isotype

Rabbit IgG

Immunogen

Synthetic peptide close to the N-terminus of human PTEN protein.

Cellular Localization

Cytoplasm

Control Tissue

Prostate Adenocarcinoma

Regulatory Rating

Research Use Only (RUO)

Entrez

5728

Storage Requirement

2-8°C

Target Molecular Weight

54 kDa

Formulation

Refer to Data Sheet

Product No: 06771050001
Product No: 06771076001

Rabbit Anti-Human PTEN Monoclonal Antibody (Clone SP170)

Instructions for Use (PDF, 83.06 KB)
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