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Picture of Rabbit Anti-Human PSMA Monoclonal Antibody (Clone SP29)

Rabbit Anti-Human PSMA Monoclonal Antibody (Clone SP29)

For research use only. Not for use in diagnostics.

Product No. Pack Size
05498368001
0.1 mL

Product No. Pack Size
05298890001
1.0 mL



PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including folylpoly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate-specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.

Figure above:
Human Prostate Carcinoma stained with anti-PSMA antibody

Contents

Rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.


IHC Performance


Human Prostate Carcinoma stained with anti-PSMA antibody

Human Prostate Adenocarcinoma stained with anti-PSMA antibody

Human Prostate Adenocarcinoma stained with anti-PSMA antibody

Human Prostate Adenocarcinoma stained with anti-PSMA antibody

Human Prostate Carcinoma stained with anti-PSMA antibody

Human Prostate Adenocarcinoma stained with anti-PSMA antibody

Human Prostate Adenocarcinoma stained with anti-PSMA antibody

Human Prostate Adenocarcinoma stained with anti-PSMA antibody



Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP29

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Bv, Dg, Ms, Pg, Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from C-terminus of human PSMA.

Cellular Localization

Membrane

Control Tissue

Prostate Carcinoma

Regulatory Rating

Research Use Only (RUO)

Entrez

2346

Storage Requirement

2-8°C

Target Molecular Weight

84 kDa

Formulation

Refer to Data Sheet

Product No: 05498368001
Product No: 05298890001

Rabbit Anti-Human PSMA Monoclonal Antibody (Clone SP29)

Instructions for Use (PDF, 68.23 KB)
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