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Rabbit Anti-Human PDHK1 Monoclonal Antibody (Clone SP270)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07746920001
0.1 mL

Product No. Pack Size
07746946001
1.0 mL


Pyruvate dehydrogenase kinase isozyme 1 (PDHK1) is a serine/threonine kinase in mitochondrial matrix for the regulation of glucose and fatty acid metabolism and homeostasis. It phosphorylates pyruvate dehydrogenase subunits PDHA1 and PDHA2 and inhibits the formation of acetyl-coenzyme A from pyruvate. PDHK1 protects cells against apoptosis and it is important for cell survival and proliferation under hypoxia.

Figure above:
Human kidney stained with anti-PDHK1 (SP270)antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human heart stained with ani-PDHK1 antibody

Human Kidney stained with anti-PDHK1 (SP270)antibody

Human Liver HCC stained with anti-PDHK1 antibody.

Human Liver stained with anti-PDHK1 antibody

Human Heart stained with ani-PDHK1 antibody

Human Kidney stained with anti-PDHK1 (SP270)antibody

Human Liver HCC stained with anti-PDHK1 antibody.

Human Liver stained with anti-PDHK1 antibody

Human Pancreas stained with ani-PDHK1 antibody

Human Stomach stained with ani-PDHK1 antibody

Human Testis stained with ani-PDHK1 antibody

Human Pancreas stained with ani-PDHK1 antibody

Human Stomach stained with ani-PDHK1 antibody

Human Testis stained with ani-PDHK1 antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP270

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

N/A

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from the C-terminus of human PDHK1 protein.

Cellular Localization

Cytoplasm

Control Tissue

Kidney

Regulatory Rating

Research Use Only (RUO)

Entrez

5163

Storage Requirement

2-8°C

Target Molecular Weight

49 kDa

Formulation

Refer to Data Sheet

Product No: 07746920001
Product No: 07746946001

Rabbit Anti-Human PDHK1 Monoclonal Antibody (Clone SP270)

Instructions for Use (PDF, 54.88 KB)
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