Log In

Please provide Log in ID
Please provide Password
Forgot password  Forgot user ID?

No Account Yet?

This website uses cookies to provide you with a more responsive and personalized service. In order to proceed to login, however, you must formally accept our cookie policy. Please read our cookie & privacy policies for more information.

Picture of Rabbit Anti-Human p53 Monoclonal Antibody (Clone SP5)

Rabbit Anti-Human p53 Monoclonal Antibody (Clone SP5)

For research use only. Not for use in diagnostics.

Product No. Pack Size
05497710001
0.1 mL

Product No. Pack Size
05298482001
1.0 mL

p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to mdm2, SV40 T antigen and human papilloma virus E6 protein. p53 senses DNA damage and possibly facilitating repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Figure above:
Human Colon Carcinoma stained with anti-p53 antibody

Contents

Rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.


IHC Performance


Human Colon Carcinoma stained with anti-p53 antibody

Human Ovarian Adenocarcinoma stained with anti-p53 antibody

Human Cervical Squamous Cell Carcinoma stained with anti-p53 antibody

Human Breast Ductal Cell Carcinoma stained with anti-p53 antibody

Human Colon Carcinoma stained with anti-p53 antibody

Human Ovarian Adenocarcinoma stained with anti-p53 antibody

Human Cervical Squamous Cell Carcinoma stained with anti-p53 antibody

Human Breast Ductal Cell Carcinoma stained with anti-p53 antibody

Human Bladder Transitional Cell Carcinoma stained with anti-p53 antibody

Human B Cell Lymphoma stained with anti-p53 antibody

Human Hepatocellular Cell Carcinoma stained with anti-p53 antibody

Human Lung Adenocarcinoma stained with anti-p53 antibody

Human Bladder Transitional Cell Carcinoma stained with anti-p53 antibody

Human B Cell Lymphoma stained with anti-p53 antibody

Human Hepatocellular Cell Carcinoma stained with anti-p53 antibody

Human Lung Adenocarcinoma stained with anti-p53 antibody

Human Stomach Adenocarcinoma stained with anti-p53 antibody

Human Stomach Adenocarcinoma stained with anti-p53 antibody



Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP5

Application

IHC-P

Species Reactivity:

 

  Tested

Hu

   Predicted by homology

Bv, Dg, Hm, Ms, Pg, Rb, Rt

Isotype

Rabbit IgG

Immunogen

Recombinant human full length wild type p53 protein.

Cellular Localization

Nucleus

Colon Carcinoma

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

7157

Storage Requirement

2-8°C

Target Molecular Weight

53 kDa

Formulation

Refer to Data Sheet

Product No: 05497710001
Product No: 05298482001

Rabbit Anti-Human p53 Monoclonal Antibody (Clone SP5)

Instructions for Use (PDF, 66.73 KB)
true