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Rabbit Anti-Human Nucleophosmin (NPM) Monoclonal Antibody (Clone SP236)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07111371001
0.1 mL

Product No. Pack Size
07111380001
1.0 mL


Nucleophosmin (NPM) is a nucleolar protein for regulating ribosome biosynthesis and centrosome duplication. The NPM gene is frequently rearranged in various types of lymphomas such as anaplastic lymphoma kinase (ALK). A C-terminal mutation occurs in acute myelogenous leukemia (AML) and prevents localization to the nucleolus, resulting in cytoplasmic distribution. NPM is frequently overexpressed in diverse solid tumors such as carcinoma of the lung and breast, colon, prostate, stomach, lymphoid and myeloid tumors.

Figure above:
Human tonsil stained with anti-nucleophosmin antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Tonsil stained with anti-nucleophosmin antibody

Human Tonsil stained with anti-nucleophosmin antibody



Flow Cytometric Analysis


Flow cytometric analysis of rabbit anti-Nucleophosmin (NPM) (SP236) antibody in Jurkat (green) compare to negative control of rabbit IgG (blue)

Flow cytometric analysis of rabbit anti-Nucleophosmin (NPM) (SP236) antibody in Jurkat (green) compare to negative control of rabbit IgG (blue)



Western Blot Analysis


Western Blot analysis of rabbit anti-Nucleophosmin (NPM) (SP236) antibody

Western Blot analysis of rabbit anti-Nucleophosmin (NPM) (SP236) antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP236

Application

IHC-P, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Bv, Ck, Ms, Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from human nucleophosmin.

Cellular Localization

 

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

4869

Storage Requirement

2-8°C

Target Molecular Weight

35 or 38 kDa

Formulation

Refer to Data Sheet

Product No: 07111371001
Product No: 07111380001

Rabbit Anti-Human Nucleophosmin (NPM) Monoclonal Antibody (Clone SP236)

Instructions for Use (PDF, 88.49 KB)
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