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Rabbit Anti-Human Kappa Light Chain Monoclonal Antibody (Clone SP148)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06974457001
0.1 mL

Product No. Pack Size
06974481001
1.0 mL


Kappa light chains are polypeptide chains resided in the cell membrane and cytoplasmic regions of normal B cells and plasma cells. The combination of kappa light chains and heavy chains forms immunoglobulin molecules. There are two classes of light chains found in immunoglobulins, kappa light chains and lambda light chains. Individual lymphoid cell only contains a single light chain class. This clonal restriction may be used to indicate the polyclonal or monoclonal nature of B cell and plasma cell populations.The ratio of kappa to lambda is about 2:1. The level of kappa or lambda can be greatly elevated in serum of patients with multiple myeloma or other B cell malignancies. **Please contact us for availability**

Figure above:
Human tonsil stained with anti-kappa light chain antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human B-Cell Lymphoma stained with anti-Kappa Light Chain antibody

Human Colon stained with anti-Kappa Light Chain antibody

Human Follicular Lymphoma stained with anti-Kappa Light Chain antibody

Human Spleen stained with anti-Kappa Light Chain antibody

Human B-Cell Lymphoma stained with anti-Kappa Light Chain antibody

Human Colon stained with anti-Kappa Light Chain antibody

Human Follicular Lymphoma stained with anti-Kappa Light Chain antibody

Human Spleen stained with anti-Kappa Light Chain antibody

Human Stomach stained with anti-Kappa Light Chain antibody

Human Tonsil stained with anti-kappa light chain antibody

Human Stomach stained with anti-Kappa Light Chain antibody

Human Tonsil stained with anti-kappa light chain antibody



Western Blot Analysis


Western Blot analysis of human spleen lysate with kappa light chain antibody

Western Blot analysis of human spleen lysate with kappa light chain antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP148

Application

IHC-P, WB

Species Reactivity

 

   Tested

Hu

   Predicted by homology

N/A

Isotype

Rabbit IgG

Immunogen

Free kappa light chain from pooled human IgG lambda myeloma sera.

Cellular Localization

Cytoplasm

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

3514

Storage Requirement

2-8°C

Target Molecular Weight

25 kDa

Formulation

Refer to Data Sheet

Product No: 06974457001
Product No: 06974481001

Rabbit Anti-Human Kappa Light Chain Monoclonal Antibody (Clone SP148)

Instructions for Use (PDF, 65.83 KB)
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