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Picture of Rabbit Anti-Human J-chain Monoclonal Antibody (Clone SP105)

Rabbit Anti-Human J-chain Monoclonal Antibody (Clone SP105)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06972969001
0.1 mL

Product No. Pack Size
06972993001
1.0 mL




J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM. **Please contact us for availability**

Figure above:
Human Tonsil stained with anti-J-chain antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Tonsil stained with anti-J-chain antibody

Human B Cell Lymphoma stained with anti-J-chain antibody

Human Colon Adenocarcinoma stained with anti-J-chain antibody

Human Colon stained with anti-J-chain antibody

Human Tonsil stained with anti-J-chain antibody

Human B Cell Lymphoma stained with anti-J-chain antibody

Human Colon Adenocarcinoma stained with anti-J-chain antibody

Human Colon stained with anti-J-chain antibody

Human HK Lymphoma stained with anti-J-chain antibody

Human Lymph Node stained with anti-J-chain antibody

Human Spleen stained with anti-J-chain antibody

Human Stomach Adenocarcinoma stained with anti-J-chain antibody

Human HK Lymphoma stained with anti-J-chain antibody

Human Lymph Node stained with anti-J-chain antibody

Human Spleen stained with anti-J-chain antibody

Human Stomach Adenocarcinoma stained with anti-J-chain antibody

Human Thymus stained with anti-J-chain antibody

Human Thyroid stained with anti-J-chain antibody

Human Thymus stained with anti-J-chain antibody

Human Thyroid stained with anti-J-chain antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP105

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Hu, Ms

Isotype

Rabbit IgG

Immunogen

Synthetic peptide near the N-terminus of human actin-beta protein.

Cellular Localization

Cytoplasm

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

3512

Storage Requirement

2-8°C

Target Molecular Weight

17 kDa

Formulation

Refer to Data Sheet

Product No: 06972969001
Product No: 06972993001

Rabbit Anti-Human J-chain Monoclonal Antibody (Clone SP105)

Instructions for Use (PDF, 65.4 KB)

Discovery XT Staining Protocol for J-chain on Mouse Small Intestine

Discovery-XT-Staining-Protocol (PDF, 81.91 KB)

Discovery XT Staining Protocol for J-chain on Human Tonsil

Discovery-XT-Staining-Protocol (PDF, 81.99 KB)
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