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Picture of Rabbit Anti-Human Glypican-3 Monoclonal Antibody (Clone SP86)

Rabbit Anti-Human Glypican-3 Monoclonal Antibody (Clone SP86)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06972217001
0.1 mL

Product No. Pack Size
06972241001
1.0 mL




Glypican-3 (GPC3) is a cell surface proteoglycan that bears heparan sulfate. It may be involved in the suppression/modulation of growth in the predominately mesodermal tissues and organs. Alteration of GPC3 expression is associated with several malignancies such as hepatocellular carcinoma (HCC). This antibody can be used to detect GPC3 in both normal and neoplastic tissue types. This antibody should not be used to differentiate hepatocellular carcinoma (HCC) from either normal liver or other types of liver disease.

Figure above:
Human Placenta stained with anti-Glypican-3 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Placenta stained with anti-Glypican-3 antibody

Human Placenta stained with anti-Glypican-3 antibody

Human Liver Hepatocellular Carcinoma stained with anti-Glypican-3 antibody

Human Placenta stained with anti-Glypican-3 antibody

Human Placenta stained with anti-Glypican-3 antibody

Human Liver Hepatocellular Carcinoma stained with anti-Glypican-3 antibody



Flow Cytometric Analysis


Flow cytometric analysis of rabbit anti-Glypican-3 (SP86) antibody in HEPG2 (green) compare to negative control of rabbit IgG (blue)
Flow cytometric analysis of rabbit anti-Glypican-3 (SP86) antibody in HEPG2 (green) compare to negative control of rabbit IgG (blue)



Western Blot Analysis


Western Blot analysis of rabbit anti-Glypican-3 (SP86) antibody
Western Blot analysis of rabbit anti-Glypican-3 (SP86) antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP86

Application

IHC-P, WB, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

N/A

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from C-terminus of human glypican-3 protein.

Cellular Localization

Membrane

Control Tissue

Placenta

Regulatory Rating

Research Use Only (RUO)

Entrez

2719

Storage Requirement

2-8°C

Target Molecular Weight

64 kDa

Formulation

Refer to Data Sheet

Product No: 06972217001
Product No: 06972241001

Rabbit Anti-Human Glypican-3 Monoclonal Antibody (Clone SP86)

Instructions for Use (PDF, 69.84 KB)
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