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Rabbit Anti-Human GIV (pY1765) Monoclonal Antibody (Clone SP158)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06974899001
0.1 mL

Product No. Pack Size
06974937001
1.0 mL


Girdin (girders of actin filements), also known as APE and GIV, is a widely expressed cytosolic protein and plays a key modulating role for the AKT-mTOR signaling pathway. Girdin is membrane-associated and interacts with phosphoinositides. Four isoforms of Girdin have been reported. GIV (pY175) is overexpressed in some human cancers such as colon, breast, and pancreatic carcinoma.

Figure above:
Human colon adenocarcinoma stained with anti-GIV (pY1765) antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Bladder stained with anti-GIV pY1765 antibody

Human Bladder Transitional Cell Carcinoma stained with anti-GIV pY1765 antibody

Human Breast Ductal Carcinoma stained with anti-GIV pY1765 antibody

Human Colon Adenocarcinoma Stage 2 stained with anti-GIV pY1765 antibody

Human Bladder stained with anti-GIV pY1765 antibody

Human Bladder Transitional Cell Carcinoma stained with anti-GIV pY1765 antibody

Human Breast Ductal Carcinoma stained with anti-GIV pY1765 antibody

Human Colon Adenocarcinoma Stage 2 stained with anti-GIV pY1765 antibody

Human Colon Adenocarcinoma Stage 3 stained with anti-GIV pY1765 antibody

Human Colon Adenocarcinoma Stage 4 stained with anti-GIV pY1765 antibody

Human Colon adenocarcinoma stained with anti-GIV (pY1765) antibody

Human Colon stained with anti-GIV pY1765 antibody

Human Colon Adenocarcinoma Stage 3 stained with anti-GIV pY1765 antibody

Human Colon Adenocarcinoma Stage 4 stained with anti-GIV pY1765 antibody

Human Colon adenocarcinoma stained with anti-GIV (pY1765) antibody

Human Colon stained with anti-GIV pY1765 antibody

Human Skin stained with anti-GIV pY1765 antibody

Human Skin stained with anti-GIV pY1765 antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP158

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

N/A

Isotype

Rabbit IgG

Immunogen

Synthetic peptide containing phosphotyrosine at 1765 of human GIV protein.

Cellular Localization

Cytoplasm, Membrane

Control Tissue

Colon adenocarcinoma

Regulatory Rating

Research Use Only (RUO)

Entrez

55704

Storage Requirement

2-8°C

Target Molecular Weight

250 kDa

Formulation

Refer to Data Sheet

Product No: 06974899001
Product No: 06974937001

Rabbit Anti-Human GIV (pY1765) Monoclonal Antibody (Clone SP158)

Instructions for Use (PDF, 50.47 KB)
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