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Picture of Rabbit Anti-Human Cyclin D3 Monoclonal Antibody (Clone SP207)

Rabbit Anti-Human Cyclin D3 Monoclonal Antibody (Clone SP207)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07071116001
0.1 mL

Product No. Pack Size
07071132001
1.0 mL




Cyclin D3 is a regulator of cell proliferation and cell-cycle progression during G1/S transition. It is a regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family. It is over-expressed or amplified in various human tumors such as acute myeloid leukemia and Burkitt’s lymphoma.

Figure above:
Human tonsil stained with anti-cyclin D3 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Tonsil stained with anti-cyclin D3 antibody

Human Uterus stained with anti-Cyclin D3 antibody

Human Skin stained with anti-Cyclin D3 antibody

Human Placenta stained with anti-Cyclin D3 antibody

Human Tonsil stained with anti-cyclin D3 antibody

Human Uterus stained with anti-Cyclin D3 antibody

Human Skin stained with anti-Cyclin D3 antibody

Human Placenta stained with anti-Cyclin D3 antibody

Human Cervix stained with anti-Cyclin D3 antibody

Human Pancreas stained with anti-Cyclin D3 antibody

Human Kidney stained with anti-Cyclin D3 antibody

Human Reactive Lymph Node stained with anti-Cyclin D3 antibody

Human Cervix stained with anti-Cyclin D3 antibody

Human Pancreas stained with anti-Cyclin D3 antibody

Human Kidney stained with anti-Cyclin D3 antibody

Human Reactive Lymph Node stained with anti-Cyclin D3 antibody

Human Cervical Squamous Cell Carcinoma stained with anti-Cyclin D3 antibody

Human B-Cell Lymphoma stained with anti-Cyclin D3 antibody

Human Cervical Squamous Cell Carcinoma stained with anti-Cyclin D3 antibody

Human B-Cell Lymphoma stained with anti-Cyclin D3 antibody



Flow Cytometric Analysis


Flow cytometric analysis of rabbit anti-Cyclin D3 (SP207) antibody in K562 (green) compare to negative control of rabbit IgG (blue)
Flow cytometric analysis of rabbit anti-Cyclin D3 (SP207) antibody in K562 (green) compare to negative control of rabbit IgG (blue)



Western Blot Analysis


Western Blot analysis of K562 cell lysate with anti-cyclin D3 antibody

Western Blot analysis of K562 cell lysate with anti-cyclin D3 antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP207

Application

IHC-P, WB, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Bv, Ms, Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived human cyclin D3 protein.

Cellular Localization

Cytoplasm, Nucleus

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

896

Storage Requirement

2-8°C

Target Molecular Weight

31 kDa

Formulation

Refer to Data Sheet

Product No: 07071116001
Product No: 07071132001

Rabbit Anti-Human Cyclin D3 Monoclonal Antibody (Clone SP207)

Instructions for Use (PDF, 177.53 KB)
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