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Rabbit Anti-Human CD35 Monoclonal Antibody (Clone SP197)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06914071001
0.1 mL

Product No. Pack Size
07071019001
1.0 mL


CD35, also known as complement receptor type 1, is a monomeric single-pass type 1 membrane glycoprotein from complement activation (RCA) family. CD35 binds complement components C3b and C4b and has an inhibitory effect on complement activation by both the classical and alternative pathways. CD35 is expressed by glomerular podocytes, follicular dendritic cells, erythrocytes, and some leukocytes. Abnormal expression of this protein has been associated with follicular dendritic cell tumor, sarcoidosis, gallbladder carcinomas, mesangiocapillary glomerulonephritis, and systemic lupus erythematosus.

Figure above:
Human kidney stained with anti-CD35 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Colon stained with anti-CD35 antibody

Human Kidney stained with anti-CD35 antibody

Human Spleen stained with anti-CD35 antibody

Human Tonsil stained with anti-CD35 antibody

Human Colon stained with anti-CD35 antibody

Human Kidney stained with anti-CD35 antibody

Human Spleen stained with anti-CD35 antibody

Human Tonsil stained with anti-CD35 antibody



Western Blot Analysis


Western Blot analysis of human tonsil lysate with anti-CD35 antibody

Western Blot analysis of human tonsil lysate with anti-CD35 antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP124

Application

IHC-P, WB

Species Reactivity

 

   Tested

Hu

   Predicted by homology

N/A

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from human CD35 protein.

Cellular Localization

Membrane

Control Tissue

Kidney, Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

1378

Storage Requirement

2-8°C

Target Molecular Weight

280 kDa

Formulation

Refer to Data Sheet

Product No: 06914071001
Product No: 07071019001

Rabbit Anti-Human CD35 Monoclonal Antibody (Clone SP197)

Instructions for Use (PDF, 63.56 KB)
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