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Picture of Rabbit Anti-Human CD278 Monoclonal Antibody (Clone SP98 )

Rabbit Anti-Human CD278 Monoclonal Antibody (Clone SP98 )

For research use only. Not for use in diagnostics.

Product No. Pack Size
06972691001
0.1 mL

Product No. Pack Size
06972721001
1.0 mL




CD278 belongs to the CD28 and CTLA-4 cell-surface receptor family and is highly expressed in activated T-cells. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.

Figure above:
Human Reactive Lymph Node stained with anti-CD278/ICOS antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Reactive Lymph Node stained with anti-CD278/ICOS antibody

Human Cervical Squamous Cell Carcinoma stained with anti-CD278/ICOS antibody

Human Endometrium stained with anti-CD278/ICOS antibody

Human HK Lymphoma stained with anti-CD278/ICOS antibody

Human Reactive Lymph Node stained with anti-CD278/ICOS antibody

Human Cervical Squamous Cell Carcinoma stained with anti-CD278/ICOS antibody

Human Endometrium stained with anti-CD278/ICOS antibody

Human HK Lymphoma stained with anti-CD278/ICOS antibody

Human Lung Adenocarcinoma stained with anti-CD278/ICOS antibody

Human Lung Squamous Cell Carcinoma stained with anti-CD278/ICOS antibody

Human Pancreatic Adenocarcinoma stained with anti-CD278/ICOS antibody

Human Thymus stained with anti-CD278/ICOS antibody

Human Lung Adenocarcinoma stained with anti-CD278/ICOS antibody

Human Lung Squamous Cell Carcinoma stained with anti-CD278/ICOS antibody

Human Pancreatic Adenocarcinoma stained with anti-CD278/ICOS antibody

Human Thymus stained with anti-CD278/ICOS antibody

Human Thyroid stained with anti-CD278/ICOS antibody

Human Tonsil stained with anti-CD278/ICOS antibody

Human Thyroid stained with anti-CD278/ICOS antibody

Human Tonsil stained with anti-CD278/ICOS antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP98

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide corresponding to C-terminus of human CD278.

Cellular Localization

Membrane

Control Tissue

Reactive Lymph Node, Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

29851

Storage Requirement

2-8°C

Target Molecular Weight

23 kDa

Formulation

Refer to Data Sheet

Product No: 06972691001
Product No: 06972721001

Rabbit Anti-Human CD278 Monoclonal Antibody (Clone SP98 )

Instructions for Use (PDF, 68.16 KB)

Discovery XT Staining Protocol for CD278/ICOS on Human Tonsil

Discovery-XT-Staining-Protocol (PDF, 46.25 KB)
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