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Rabbit Anti-Human CD21 Monoclonal Antibody (Clone SP186)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06914667001
0.1 mL

Product No. Pack Size
06914683001
1.0 mL


CD21 antigen, also known as complement receptor type 2 (CR2), is a glycoprotein and a receptor for the C3d fragment of complement component 3. It is predominantly expressed in follicular dendritic cells and B lymphocytes. CD21 binds to CD19, and CD81 to form a B cell complex on mature B cells and enhances the B cell response to antigen through C3d.

Figure above:
Human tonsil stained with anti-CD21 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Colon stained with anti-CD21 antibody

Human Reactive Lymph Node stained with anti-CD21 antibody

Human Spleen stained with anti-CD21 antibody

Human Tonsil stained with anti-CD21 antibody

Human Colon stained with anti-CD21 antibody

Human Reactive Lymph Node stained with anti-CD21 antibody

Human Spleen stained with anti-CD21 antibody

Human Tonsil stained with anti-CD21 antibody



Flow Cytometric Analysis


Flow cytometric analysis of rabbit anti-CD21 (SP186) antibody in Raji (green) compare to negative control of rabbit IgG (blue)

Flow cytometric analysis of rabbit anti-CD21 (SP186) antibody in Raji (green) compare to negative control of rabbit IgG (blue)



Western Blot Analysis


Western Blot analysis of Daudi cell lysate with anti-CD21 antibody


Western Blot analysis of Daudi cell lysate with anti-CD21 antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP186

Application

IHC-P, WB, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Ms

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from the C-terminus of human CD21 protein.

Cellular Localization

Membrane

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

1380

Storage Requirement

2-8°C

Target Molecular Weight

155 kDa

Formulation

Refer to Data Sheet

Product No: 06914667001
Product No: 06914683001

Rabbit Anti-Human CD21 Monoclonal Antibody (Clone SP186)

Instructions for Use (PDF, 73.82 KB)
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