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Picture of Rabbit Anti-Human CD169 Monoclonal Antibody (Clone SP216)

Rabbit Anti-Human CD169 Monoclonal Antibody (Clone SP216)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07074298001
0.1 mL

Product No. Pack Size
07074310001
1.0 mL


CD169 or sialoadhesin is a cell adhesion molecule on the surface of some macrophages distributed in the spleen, liver, lymph node, bone marrow, colon, lung, and various inflammatory tissues. It acts as an endocytic receptor mediating clathrin-dependent endocytosis. CD169 predominately binds to neutrophils, but can also bind to monocytes, natural killer cells, B cells and a subset of cytotoxic T cells by interacting with sialic acid molecules on their surfaces of their ligands.

Figure above:
Human lymph node stained with anti-CD169 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Bone Marrow stained with anti-CD169 antibody

Human Cervical Squamous Cell Carcinoma stained with anti-CD169 antibody

Human HK Lymphoma stained with anti-CD169 antibody

Human Lung Squamous Cell Carcinoma stained with anti-CD169 antibody

Human Bone Marrow stained with anti-CD169 antibody

Human Cervical Squamous Cell Carcinoma stained with anti-CD169 antibody

Human HK Lymphoma stained with anti-CD169 antibody

Human Lung Squamous Cell Carcinoma stained with anti-CD169 antibody

Human Lung stained with anti-CD169 antibody

Human Lymph node stained with anti-CD169 antibody

Human Lung stained with anti-CD169 antibody

Human Lymph node stained with anti-CD169 antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP216

Application

IHC-P

Species Reactivity

 

   Tested

Hu

   Predicted by homology

N/A

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from the internal region of human CD169 protein.

Cellular Localization

Membrane

Control Tissue

Liver, Lung, Lymph Node

Regulatory Rating

Research Use Only (RUO)

Entrez

6614

Storage Requirement

2-8°C

Target Molecular Weight

182 kDa

Formulation

Refer to Data Sheet

Product No: 07074298001
Product No: 07074310001

Rabbit Anti-Human CD169 Monoclonal Antibody (Clone SP216)

Instructions for Use (PDF, 60.14 KB)
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