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Picture of Rabbit Anti-Human Carbonic Anhydrase 9 (CA-9) Monoclonal Antibody (Clone SP106)

Rabbit Anti-Human Carbonic Anhydrase 9 (CA-9) Monoclonal Antibody (Clone SP106)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06973027001
0.1 mL

Product No. Pack Size
06973019001
1.0 mL




Carbonic anhydrase (CA) is an enzyme that assists rapid inter-conversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that are inducible by hypoxia, via HIF-1 alpha. CA-9 is one of the most inducible genes because of its stability and location within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CA 9 results in increased cell death under hypoxia. Therefore, CA-9 has become a reliable histochemical marker of hypoxia. **Please contact us for availability**

Figure above:
Human Stomach stained with anti-Carbonic Anhydrase 9 (CA-9) antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Stomach stained with anti-Carbonic Anhydrase 9 (CA-9) antibody

Human Stomach stained with anti-Carbonic Anhydrase 9 (CA-9) antibody2

Human Stomach stained with anti-Carbonic Anhydrase 9 (CA-9) antibody

Human Stomach stained with anti-Carbonic Anhydrase 9 (CA-9) antibody2



Flow Cytometric Analysis


Flow cytometric analysis of rabbit anti-CA-9 (SP106) antibody in HT29 (green) compare to negative control of rabbit IgG (blue)
Flow cytometric analysis of rabbit anti-CA-9 (SP106) antibody in HT29 (green) compare to negative control of rabbit IgG (blue)


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP106

Application

IHC-P, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Pg

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from human CA-9.

Cellular Localization

Membrane, Nucleus

Control Tissue

Stomach

Regulatory Rating

Research Use Only (RUO)

Entrez

768

Storage Requirement

2-8°C

Target Molecular Weight

50 kDa

Formulation

Refer to Data Sheet

Product No: 06973027001
Product No: 06973019001

Rabbit Anti-Human Carbonic Anhydrase 9 (CA-9) Monoclonal Antibody (Clone SP106)

Instructions for Use (PDF, 83.68 KB)
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