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Picture of Rabbit Anti-Human Calpain Monoclonal Antibody (Clone SP81)

Rabbit Anti-Human Calpain Monoclonal Antibody (Clone SP81)

For research use only. Not for use in diagnostics.

Product No. Pack Size
06971997001
0.1 mL

Product No. Pack Size
06972039001
1.0 mL



Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Calpain S1 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.

Figure above:
Human Breast Carcinoma stained with anti-Calpain antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human Breast Ductal Carcinoma stained with anti-Calpain antibody

Human Stomach Adenocarcinoma stained with anti-Calpain antibody

Human Uterus stained with anti-Calpain antibody

Human Prostate Adenocarcinoma stained with anti-Calpain antibody

Human Breast Ductal Carcinoma stained with anti-Calpain antibody

Human Stomach Adenocarcinoma stained with anti-Calpain antibody

Human Uterus stained with anti-Calpain antibody

Human Prostate Adenocarcinoma stained with anti-Calpain antibody

Human Lung Adenocarcinoma stained with anti-Calpain antibody

Human Breast stained with anti-Calpain antibody

Human Bladder stained with anti-Calpain antibody

Human Bladder Transitional Cell Carcinoma stained with anti-Calpain antibody

Human Lung Adenocarcinoma stained with anti-Calpain antibody

Human Breast stained with anti-Calpain antibody

Human Bladder stained with anti-Calpain antibody

Human Bladder Transitional Cell Carcinoma stained with anti-Calpain antibody

Human Fallopian Tube stained with anti-Calpain antibody

Human Pancreas stained with anti-Calpain antibody

Human Fallopian Tube stained with anti-Calpain antibody

Human Pancreas stained with anti-Calpain antibody



Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP81

Application

IHC-P, WB

Species Reactivity

 

   Tested

Hu, Ms

   Predicted by homology

Fg, Ms, Pg, Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from internal region of human calpain protein.

Cellular Localization

Cytoplasm

Control Tissue

Breast Carcinoma

Regulatory Rating

Research Use Only (RUO)

Entrez

826

Storage Requirement

2-8°C

Target Molecular Weight

28 kDa

Formulation

Refer to Data Sheet

Product No: 06971997001
Product No: 06972039001

Rabbit Anti-Human Calpain Monoclonal Antibody (Clone SP81)

Instructions for Use (PDF, 61.51 KB)

Discovery XT Staining Protocol for Calpain on Mouse Liver

Discovery-XT-Staining-Protocol (PDF, 81.66 KB)

Discovery XT Staining Protocol for Calpain on Human Breast Carcinoma

Discovery-XT-Staining-Protocol (PDF, 81.39 KB)
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