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Picture of Rabbit Anti-Human B7-H3/CD276 Monoclonal Antibody (Clone SP206)

Rabbit Anti-Human B7-H3/CD276 Monoclonal Antibody (Clone SP206)

For research use only. Not for use in diagnostics.

Product No. Pack Size
07071035001
0.1 mL

Product No. Pack Size
07071051001
1.0 mL




CD276 (also known as B7-H3) is a membrane protein that participates in the regulation of T cell-mediated immune response. It is expressed widely in dendritic cells, some epithelial cells, trophoblast cells, Hofbauer cells of the placenta, activated B and T cells, NK cells, and monocytes. CD276 is also expressed by some solid tumors such as melanoma, prostate cancer, and pancreatic cancer.

Figure above:
Human tonsil stained with anti-CD276 antibody

Contents

Rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.


IHC Performance


Human tonsil stained with anti-CD276 antibody

Human Testis stained with anti-B7-H3 antibody

Human Stomach Adenocarcinoma stained with anti-B7-H3 antibody

Human Lung stained with anti-B7-H3 antibody

Human tonsil stained with anti-CD276 antibody

Human Testis stained with anti-B7-H3 antibody

Human Stomach Adenocarcinoma stained with anti-B7-H3 antibody

Human Lung stained with anti-B7-H3 antibody

Human Lung Adenocarcinoma stained with anti-B7-H3 antibody

Human Lung SCCa stained with anti-B7-H3 antibody

Human Colon stained with anti-B7-H3 antibody

Human Colon Adenocarcinoma stained with anti-B7-H3 antibody

Human Lung Adenocarcinoma stained with anti-B7-H3 antibody

Human Lung SCCa stained with anti-B7-H3 antibody

Human Colon stained with anti-B7-H3 antibody

Human Colon Adenocarcinoma stained with anti-B7-H3 antibody

Human Breast stained with anti-B7-H3 antibody

Human Breast Ductal Carcinoma stained with anti-B7-H3 antibody

Human Stomach stained with anti-B7-H3 antibody

Human Breast stained with anti-B7-H3 antibody

Human Breast Ductal Carcinoma stained with anti-B7-H3 antibody

Human Stomach stained with anti-B7-H3 antibody




Flow Cytometric Analysis


Flow cytometric analysis of rabbit anti-B7-H3_CD276 (SP206) antibody in 293 (green) compare to negative control of rabbit IgG (blue)
Flow cytometric analysis of rabbit anti-B7-H3_CD276 (SP206) antibody in 293 (green) compare to negative control of rabbit IgG (blue)



Western Blot Analysis


Western Blot analysis of 293T cell lysate with anti-CD276 antibody

Western Blot analysis of 293T cell lysate with anti-CD276 antibody


Product Details:


Technology

Rabbit Monoclonal

Clone Name

SP206

Application

IHC-P, WB, FACS

Species Reactivity

 

   Tested

Hu

   Predicted by homology

Ms, Rt

Isotype

Rabbit IgG

Immunogen

Synthetic peptide derived from human B7-H3 protein.

Cellular Localization

Membrane

Control Tissue

Tonsil

Regulatory Rating

Research Use Only (RUO)

Entrez

80381

Storage Requirement

2-8°C

Target Molecular Weight

110 kDa

Formulation

Refer to Data Sheet

Product No: 07071035001
Product No: 07071051001

Rabbit Anti-Human B7-H3/CD276 Monoclonal Antibody (Clone SP206)

Instructions for Use (PDF, 75.22 KB)
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